SFB796   -   Projects and Principal investigators

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Project
code
Principal
investigator
Title Institute Email Phone
A1 Ulrich Schubert Interaction of the HIV-1 regulatory virus protein R (Vpr) with host cell factors (sub project concluded) (sub project concluded) (sub project concluded)
A2 Heinrich Sticht Computational analysis of linear interaction motifs and globular protein interfaces in effector proteins Inst. f. Biochemie
Abt. Bioinformatik
Fahrstr. 17
91054 Erlangen
H.Sticht (at) biochem.uni-erlangen.de +49(0)91318524614
A3 Yves Muller Structural biology of plant potyvirus and cytomegalovirus effector proteins Department Biologie
LS Biotechnik
Henkestr. 91 (IZMP)
91052 Erlangen
ymuller (at) biologie.uni-erlangen.de +49(0)91318523081
A4 Thomas Wittenberg Automated multi-dimensional, high-content image-analysis for fluorescence-microscopy Fraunhofer-Institut (IIS)
Abt. BMT
Am Wolfsmantel 33
91058 Erlangen
thomas.wittenberg (at) iis.fraunhofer.de +49(0)91317767330
A5 Jutta Eichler Exploration of the struct. basis for the functional mimicry of the CD4 binding site of HIV-1 gp120: Implications for virus entry inhibition and the induction of broadly neutralizing antibodies (sub project concluded) (sub project concluded) (sub project concluded)
A6 Nuska Tschammer Functional selectivity as a result of viral chemokine receptor heteromerization Dep. of Chemistry and Pharmacy
Emil Fischer Center
Schuhstr. 19
91052 Erlangen
nuska.tschammer (at) fau.de +49(0)91318523931
B1 Armin Ensser STAT-Activation in T-cell growth transformation Inst. f. Klinische u. Molekulare Virologie Schlossgarten 4
91054 Erlangen
Armin.Ensser (at) viro.med.uni-erlangen.de +49(0)91318522101
B2 Alexander Steinkasserer Control of HSV-1 specific replication and transmission mechanisms in human dendritic cells Dermatologische Klinik
Universitätsklinikum
Hartmannstr. 14
91052 Erlangen
alexander.steinkasserer (at) uk-erlangen.de +49(0)91318536725
B3 Thomas Stamminger Interference of the viral effector proteins pp71 and IE1 with ND10-mediated intrinsic immunity against human cytomegalovirus infections Inst. f. Klinische u. Molekulare Virologie Schlossgarten 4
91054 Erlangen
thomas.stamminger (at) viro.med.uni-erlangen.de +49(0)91318526783
B4 Sophia Sonnewald Reprogramming of plant metabolism by the type III effector XopB from Xanthomonas campestris pv. vesicatoria (sub project concluded) (sub project concluded) (sub project concluded)
B5 Andreas Burkovski Analysis of virulence factors of Corynebacterium diphtheriae (sub project concluded) (sub project concluded) (sub project concluded)
B6 Roland Lang Reprogramming of macrophages by the mycobacterial cord factor Inst. f. Mikrobiologie
Universitätsklinikum
Wasserturmstr. 3-5
91054 Erlangen
Roland.Lang (at) uk-erlangen.de +49(0)91318522979
B7 Stefan Wirtz
Markus Neurath
Functional analysis of bacterial Type VI effectors in EBI3-dependent regulation of enteric infection and inflammation Medizinische Klinik I
Universitätsklinikum Erlangen
Stefan.Wirtz (at) uk-erlangen.de
Markus.Neurath (at) uk-erlangen.de
+49(0)91318535882
B8 Anja Lührmann Functional analysis of Coxiella burnetii type IV effector-induced inhibition of host cell apoptosis Inst. f. Mikrobiologie
Universitätsklinikum
Wasserturmstr. 3-5
91054 Erlangen
anja.luehrmann (at) uk-erlangen.de +49(0)91318522577
B9 Christoph Becker
Michael Stürzl
Viral regulators of the cellular ripoptosome protein complex Universitätsklinikum
Medizinische Klinik I bzw.
Chirurgische Klinik
christoph.becker (at) uk-erlangen.de
michael.stuerzl (at) uk-erlangen.de
+49(0)91318535886 bzw.
+49(0)91318539520
B10 Steffen Backert Molecular function and signal transduction of the serine protease HtrA, a novel secreted effector protein of bacterial pathogens Department Biologie
LS Mikrobiologie
Staudtstr. 5
91058 Erlangen
Steffen.Backert (at) biologie.uni-erlangen.de +49(0)91318528081
C1 Michael Hensel The structural and functional basis of reprogramming of vesicular transport by Salmonella enterica effector proteins (sub project concluded) (sub project concluded) (sub project concluded)
C2 Uwe Sonnewald Functional analysis of the interaction between host factors and viral transport proteins Department Biologie
LS Biochemie
Staudtstr. 5
91058 Erlangen
usonne (at)
biologie.uni-erlangen.de
+49(0)91318528256
C3 Manfred Marschall Regulation of nuclear egress of human cytomegalovirus through a multifunctional viral-cellular protein complex Inst. f. Klinische u. Molekulare Virologie Schlossgarten 4
91054 Erlangen
manfred.marschall (at) viro.med.uni-erlangen.de +49(0)91318526783
C4 Christian Berens In vivo expression analysis of virulence proteins of Salmonella thyphimurium in macrophages and mouse models (sub project concluded) (sub project concluded) (sub project concluded)
C5 Frederik Börnke Functional characterisation of bacterial type III effectors targeting host cell vesicle trafficking (sub project concluded) (sub project concluded) (sub project concluded)
C6 Andrea Thoma-Kreß Effects of Tax and p8 proteins on cell-to-cell transmission of Human T-cell lymphotropic virus type 1 (HTLV-1) Inst. f. Klinische u. Molekulare Virologie Schlossgarten 4
91054 Erlangen
andrea.kress (at) viro.med.uni-erlangen.de +49(0)91318526429
C7 Benedikt Kost Modulation of cellular processes and Rac/Rop (Rho) activity in Arabidopsis by Pto TTSS effector proteins Department Biologie
LS Zellbiologie
Staudtstr. 5
91058 Erlangen
bkost (at) biologie.uni-erlangen.de +49(0)91318528216